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Recent Publications
Brown University William Trenkle  
Christopher T. Seto 1.“Peptidic a-Ketocarboxylic Acids and Sulfonamides as Inhibitors of Protein Tyrosine Phosphatases” Chen, Y. T.; Xie, J.; Seto, C. T. J. Org. Chem. 2003, 68, 4123.

2.“Divalent and Trivalent a-Ketocarboxylic Acids as Inhibitors of Protein Tyrosine Phosphatases” Chen, Y. T.; Seto, C. T. J. Med. Chem. 2002, 45, 3946.
Columbia University Samuel Danishefsky
 		 1."The Total Synthesis of Rishirilide B," J.G. Allen and S.J. Danishefsky, J. Am. Chem. Soc., 123, 351­352 (2001)

2. "Pursuit of Optimal Carbohydrate-Based Anticancer Vaccines: Preparation of a Multi-Antigenic Unimolecular Glycopeptide Containing the Tn, MBr1 and Lewisy Antigens," J.R. Allen, C.R. Harris, and S.J. Danishefsky, J. Am. Chem. Soc., 123, 1890­1897 (2001)

3. "Total Synthesis and Determination of the Absolute Configuration of Frondosin B," M. Inoue, M. Carson, A. Frontier, and S.J. Danishefsky, J. Am. Chem. Soc., 123, 1878­1889 (2001)

Gilbert Stork
 		  
Ronald Breslow 1. R. Breslow, "Determining the Geometries of Transition States by Use of Antihydrophobic Additives in Water", Accts. Chem. Res. 3, 471-478 (2004).

2. L. Liu, W. Zhou, J. J. Chruma, and R. Breslow "Transamination Reactions with Multiple Turnovers Catalyzed by Hydrophobic Pyridoxamine Cofactors in the Presence of Polyethylenimine Polymers", J. Amer. Chem. Soc. 126,  8136-8137 (2004).
Virginia Cornish 1. H. Lin, H. Tao, V.W. Cornish.  "Directed Evolution of a Glycosynthase Via Chemical Complementation."  J. Am. Chem. Soc., 126, 15051-15059 (2004).  Featured in Chem. & Eng. News, 82: 46, 32 (2004). 

2. L. Miller, J. Sable, P. Goelet, M. Sheetz, V.W. Cornish.  "Methotrexate Conjugates: A Molecular In Vivo Protein Tag."  Angew. Chem., 116, 1704-1707 (2004); Angew. Chem. Int. Ed., 43, 1672-1675 (2004).

3. A. Forster, Z. Tan, M. N. L. Nalam, H. Lin, H. Qu, V.W. Cornish, S. Blacklow.  "Programming peptidomimetic syntheses by translating genetic codes designed de novo."  Proc. Natl. Acad. Sci. USA, 100, 6353-6357 (2003)  Featured in Chem. Biol., 10, 586-587 (2003) and in Chem. & Eng. News, 82:3, 64-68 (2004). 
Thomas Katz
 		 1. "Olefin Metatheses and Related Reactions Initiated by Carbene Derivatives of Metals in Low Oxidation States," T. J. Katz, Angew. Chem. 117, DOI: 10.1002/ange.200462442 (2005); Angew. Chem. Int. Ed. 44, DOI: 10.1002/anie.200462442 (2005).

2. "Fischer Metal Carbenes and Olefin Metathesis," T. J. Katz, In Handbook of Metathesis; R. H. Grubbs, Ed.; Wiley-VCH: Weinheim, Germany, 2003; Volume 1, Chapter 5.
James Leighton 1."Formal Total Synthesis of Mycoticin A," S.D. Dreher and J.L. Leighton, J. Am. Chem. Soc., 123, 341­342 (2001)

2. "Total Synthesis of Leucascandrolide A," K.R. Hornberger, C.L. Hamblett, and J.L. Leighton, J. Am. Chem. Soc., 122, 12894­12895 (2000)
Koji Nakanishi 1. Porphyrins as Photosensitizers to Enhance Night Vision, I. Washington, C. Brooks, Turro, N. and K. Nakanishi, J. Am. Chem, Soc.126, 9892-98, (2004).

2.Chemistry and Biology of Terpene Trilactones from Ginkgo Biloba.  K. Stromgaard and K. Nakanishi. Angew. Chem. Int. Ed.43, 1640-1658 (2004).
Colin Nuckolls "Enforced Stacking in Crowded Arenes," M.L. Bushey, A. Hwang, P.W. Stephens, and C. Nuckolls, J. Am. Chem. Soc., 123, 8157 (2001)
Dalibor Sames "Selective Functionalization of Amino Acids in Water: A Synthetic Method via Catalytic C-H Bond Activation," B.D. Dangel, J.A. Johnson, and D. Sames, J. Am. Chem. Soc., 123, 8149­8150 (2001)
Brent Stockwell Waldemar Adam,, Sara G. Bosio, Nicholas J. Turro, and Barbara T. Wolff "Enecarbamates as Selective Substrates in Oxidations: Chiral-Auxiliary Controlled Mode Selectivity and Diastereoselectivity in the [2+2] Cycloaddition and Ene Reaction of Singlet Oxygen and in the Epoxidation by DMD and mCPBA" Journal of Organic Chemistry 69, 1704-1715 (2004)

Steffen Jockusch, Rex X. Ren, Young Pyo Jang, Yasuhiro Itagaki, Heidi R. Vollmer-Snarr, Janet R. Sparrow, Koji Nakanishi, and Nicholas J. Turro "Photochemistry of A1E, a Retinoid with a Conjugated Pyridinium Moiety: Competition between Pericyclic Photooxygenation and Pericyclization" Journal of the American Chemical Society 126, 4646-4652 (2004)

T. Poon, J. Sivaguru, R. Franz, S. Jockusch, C. Martinez, I. Washington, W. Adam, Y. Inoue, and N.J. Turro, “Temperature and Solvent Control of the Stereoselectivity in the Reactions of Singlet Oxygen with Oxazolidinone-Substituted Enecarbamates,” J. Am. Chem. Soc., 126, 10498-10499 (2004).

Cornell University John E. McMurry Professor McMurry retired June 30, 2004. Professor McMurry is currently engaged in writing chemistry textbooks.
Tadhg P.  Begley Settembre, E. C.; Dorrestein, P. C.; Zhai, H.; Chatterjee, A.; McLafferty, F. W.; Begley, T. P.; Ealick, S.E. Thiamin Biosynthesis in Bacillus subtilis: Structure of the Thiazole Synthase/Sulfur carrier protein. Biochemistry 2004, 43, 11647.

Begley, T. P.; Ealick, S. E. Enzymatic reactions involving novel mechanisms of carbanion stabilization. Current Opinion in Chemical Biology 2004, 8, 508.

Strauss, E; Zhai, H; Brand, L. A.; McLafferty, F. W.; Begley, T. P. Mechanistic Studies on Phosphopantothenoylcysteine Decarboxylase: Trapping of an Enethiolate Intermediate with a Mechanism-Based Inactivating Agent. Biochemistry 2004, 43, 15520.

 Lawhorn, B.; Mehl, R.; Begley, T. Biosynthesis of the thiamin pyrimidine: the reconstitution of a remarkable rearrangement reaction. Organic and Biomolecular Chemistry 2004, 2, 2538.
Barry K. Carpenter Cremeens, M. E.; Carpenter, B. K. Access to an Excited State via the Thermal Ring-opening of a Cyclopropylidene. Org. Lett. 2004, 6, 2349.
Paul J. Chirik Pool, J. A.; Lobkovsky, E.; Chirik, P. J. "Hydrogenation and cleavage of dinitrogen to ammonia with a well-defined zirconium complex." Nature 2004, 427, 527-530.

Bernskoetter, W. H.; Lobkovsky, E.; Chirik, P. J. "Synthesis of a -diiminate iridium tetrahydride for arene C-H bond activation." Chem. Comm. 2004, 763-764.

Bradley, C. A.; Lobkovsky, E.; Chirik, P. J. "Synthesis of a zirconium sandwich complex and crystallographic characterization of its adduct with tetrahydrofuran." J. Am. Chem. Soc. 2003, 125, 8110-8111.
Geoffrey W. Coates

Byrne, C. M.; Allen, S. D.; Lobkovsky, E. B.; Coates, G. W. "Alternating Copolymerization of Limonene Oxide and Carbon Dioxide" J. Am. Chem. Soc., 2004, in press.

Qin, Z.; Thomas, C. M.; Lee, S.; Coates, G. W. “Cobalt-Based Complexes for the Copolymerization of Propylene Oxide and CO2: Active and Selective Catalysts for Polycarbonate Synthesis” Angew. Chem. Int. Ed. 2003, 42, 5484 –5487.

Moore, D. R.; Cheng, M.; Lobkovsky, E. B.; Coates, G. W. “Mechanism of the Alternating Copolymerization of Epoxides and CO2 using beta-Diiminate Zinc Catalysts: Evidence for a Bimetallic Epoxide Enchainment” J. Am. Chem. Soc. 2003, 125, 11911-11924.
David B. Collum Lithium Hexamethyldisilazide/Triethylamine-Mediated Ketone Enolization: Remarkable Rate Accelerations Stemming from a Dimer-Based Mechanism. Zhao, P.; Collum, D. B. J. Am. Chem. Soc. 2003, 125, 4008

"BF3-Mediated Additions of Organolithiums to Ketimines: X-ray Crystal Structures of BF3-Ketimine Complexes". Yun, Ma; Lobkovsky, E.; Collum, D.B. J. Org. Chem. 2005, 70, 2335.
Bruce  Ganem G. Zhao, U. C. Deo, B. Ganem, "Selective Fowler Reductions: Asymmetric Total Syntheses of 1sofagomine and Other 1-Azasugars from Methyl Nicotinate," Org. Lett. 2001, 3, 201.

M. A. Clark,, Q. Wang, B. Ganem, "Oxidation of Bicyclic Oxazolidines: Applications to Glycomimetics and Novel Saccharide Derivatives," Tetrahedron Lett. 2002, 43, 347.

Q. Xia, B. Ganem, "An Efficient Synthesis of Substituted Prolines by the Selective Reduction and Reductive Cyanation of 2-Pyrrolidones," Tetrahedron Lett. 2002, 43, 1597.

D. S. Hamilton, Z. Ding, B. Ganem, D. J. Creighton, "Glutathionyl Transferase-Catalyzed Addition of Glutathione to COMC: A New Hypothesis for Antitumor Activity," Org. Lett. 2002, 4, 1209
Stephen  Lee
  1. "Transition metal AB3 intermetallics: structure maps based on quantum mechanical stability." Peter Michael Clark, Stephen Lee and Daniel C. Fredrickson. J. Solid State Chem. 2005, in press.
  2. "Small Amphiphilic Organics, Coordination Extended Solids, and Constant Curvature Structure" Stephen Lee, Abhijit Basu Mallik, Zhengtao Xu, Emil B. Lobkovsky, and Lieu Tran. Accounts of Chemical Research 2005, in press.
  3. "Three Trigonal Coordination Extended Solids with Gyroid and Lamellar Topology" Abhijit Basu Mallik, Stephen Lee and Emil Lobkovsky. Crystal Growth and Design 2005 in press, ASAP
D. Tyler  McQuade
  • “A Cross-Linked Reverse Micelle-Encapsulated Palladium Catalyst” K.E. Price, D.T. McQuade Chem. Comm., 2005, 1714-1716.
  • “Baylis-Hillman Mechanism: A New Interpretation in Apolar Solvents” K.E. Price, S.J. Broadwater, H.M. Jung, D.T. McQuade Org. Lett. 2005, 7, 147-150.
  • “A Comparison of Crystalline- and Grafted Polymer-Based Chemosensors”  S.J. Broadwater, M.K. Hickey, D.T. McQuade J. Am. Chem. Soc. 2003 125, 11154-11155.
  • “Synthesis and Characterization of Cross-Linked Reverse Micelles” H.M. Jung, K.E. Price, D.T. McQuade J. Am. Chem. Soc. 2003, 125, 5351-5355.
Jerrold  Meinwald Synthesis of Macrocyclic Insect-Derived Alkaloids. Jay J. Farmer, Frank C. Schroeder, Jerrold Meinwald, Helv. Chim. Acta 2000, 83, 2594-2606.

Chiral Silylation Reagents for the Determination of Absolute Configuration by NMR Spectroscopy. Douglas B. Weibel, Tameka R. Walker, Frank C. Schroeder, Jerrold Meinwald, Organic Letters 2000, 2, 2381-2383.

A Combinatorial Library of Macrocyclic Polyamines Produced by a Ladybird Beetle. F. C. Schroeder, J. J. Farmer, A. B. Attygalle, S. R. Smedley, T. Eisner, and J. Meinwald, J. Am. Chem. Soc. 2000, 122, 3628-3634.

Jón T.  Njarðarson Njardarson, J. T.; Gaul, C.; Shan, D.; Huang, X.-Y.; Danishefsky, S. J. Discovery of Potent Cell Migration Inhibitors through Total Synthesis: Lessons from Structure-Activity Studies of (+)-Migrastatin J. Am. Chem. Soc. 2004, 126, 1038.

Spiegel, D. A.; Njardarson, J. T.; McDonald, I.; Wood, J. L. Innovation and Art in Organic Chemistry: Synthetic Efforts Toward the Phomoidrides Chem. Rev. 2003, 103, 2691.

Gaul, C.; Njardarson, J. T.; Danishefsky, S. J. The Total Synthesis of (+)-Migrastatin J. Am. Chem. Soc. 2003, 125, 6042.
Dotsevi Y. Sogah  
David A.  Usher  
Derek S. Tan
Tan, D. S. "Diversity-oriented synthesis: Exploring the intersections between chemistry and biology." Nature Chem. Biol. 2005, 1, 74–84.
Ferreras, J. A.; Ryu, J.-S.; Di Lello, F.; Tan, D. S., Quadri, L. E. N. "Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersnina pestis." Nature Chem. Biol. 2005, 1, 29–32.
Shang, S.; Tan, D. S. "Advancing chemistry and biology through diversity-oriented synthesis of natural product-like libraries." Curr. Opin. Chem. Biol. 2005, 9, 248–258.
 DiBlasi, C. M.; Macks, D. E.; Tan, D. S. "An acid-stable tert-butyldiarylsilyl (TBDAS) linker for solid-phase organic synthesis." Org. Lett. 2005, 7, 1777–1780.
Moilanen, S. B.; Tan, D. S. "Enantioselective synthesis of erythro-4-deoxyglycals as scaffolds for target- and diversity-oriented synthesis: New insights into glycal reactivity." Org. Biomol. Chem. 2005, 3, 798–803.
Dartmouth College Peter A. Jacobi “Iterative Synthesis of Semicorrins, Tripyrrolines and Higher Analogs,” Jacobi, P.A.; Liu, H. J. Am. Chem. Soc. 1999, 121, 1958. (b) “Studies on Corrin Synthesis. A Solution to the Introduction of Meso Substituents,” Jacobi, P.A.; Liu, H. J. Org. Chem. 1999, 64, 1778. (c) “Synthesis of 1,2,3,7,8,9-Hexahydropyrrins and Secocorrins; Important Precursors for the Construction of Corrins,” Jacobi, P.A.; Liu, H. Organic Letters 1999, 1, 341. (d) “On the Mechanism of Pd(0)-Initiated Coupling-Cyclization of g-Aminoalkynes,” Jacobi, P.A.; Liu, H. J. Org. Chem. 2000, 65, 7676. (e) "Synthesis of Porphobilinogen via a Novel Ozonide Cleavage Reaction," Jacobi, P.A.; Li, Y. J. Am. Chem. Soc. 2001, 123, 9307. (f) "Lewis Acid-Promoted Oxidative Addition of Thioimidates to Pd(0),ä Ghosh, I.; Jacobi, P.A. J. Org. Chem. 2002

Amy C. Anderson
  • O'Neil, R., Lilien, R., Donald, B., Stroud, R. and Anderson, A. "Phylogenetic classification of protozoa based on the structure of the linker domain in the bifunctional enzyme, dihydrofolate reductase-thymidylate synthase", J. Biol. Chem., 278: 52980-52987 (2003).
  • O'Neil, R., Lilien, R., Donald, B., Stroud, R. and Anderson, A. "The Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Reveals a Novel Architecture for the Bifunctional Enzyme", J. Eukaryot. Microbiol. 50: 555S-556S (2003).
  • Anderson, A."The Process of Structure-based Drug Design", Chem. & Biol. 10, 787-797 (2003).
Gordon W. Gribble

"Partial Synthesis of 23-Hydroxyursolic Acid Isolated from Medicinal Plants of the Rubiaceae Family"; Bore, L.; Honda, T.; Gribble, G.W. Nat. Prod. Lett. 2002, 16, 273-276.

"Novel Triterpenoid CDDO-Me is a Potent Inducer of Apoptosis and Differentiation in Acute Myelogenous Leukemia"; Konopleva, M.; Tsao, T.; Ruvolo, P.; Stiouf, I.; Estrov, Z.; Leysath, C.; Zhao, S.; Harris, D.; Chang, S.; Jackson, C.E.; Munsell, M.; Suh, N.; May, W.S.; Honda, T.; Gribble, G.W.; Sporn, M.B.; Andreeff, M. Blood 2002, 99, 326-335.

"Synthesis and Diels-Alder Reactions of the Furo[3,4-b]pyrrole Ring System. A New Indole Ring Synthesis"; Moskalev, N.V.; Gribble, G.W. Tetrahedron Lett. 2002, 43,197-201.

"A Convenient Synthesis of the Furo[3,4-b]indole Ring System"; Gribble, G.W.; Jiang, J.; Liu, Y. J. Org. Chem. 2002, 67, 1001-1003.

"Synthesis of the New Natural Heptachloro 1-Methyl-1',2-bipyrrole Q1"; Jun, W.; Vetter, W.; Gribble, G.W.; Schneekloth, J.S. Jr.; Blank, D.H.; Gorls, H., Angew. Chem. Int. Ed., 2002, 41, 1740-1743.

"A Direct Lithiation Route to 2-Acylindoles"; Jiang, J.; Gribble, G.W.; Synth. Commun. 2002, 32, 2035-2040.

"A Simple Synthesis of Pyrrolo[3,4-b]indoles from 2,3-Dimethylindole"; Kishbaugh, T.L.S.; Gribble, G.W.; Synth. Commun. 2002, 32, 2003-2008.

David M. Lemal
  • Lombardi, P.J., Gan, Y., Lemal, D.M. "Synthesis and Chemistry of Highly Fluorinated Oxepane-2,7-diols", Coll. Czech. Chem. Commun., in press.
  • He, Yigang, Lemal, D.M. "A Photoprecursor for Difluorocarbene", J. Fluorine Chem., in press.
  • Lou, Y., Chang, J., Jorgensen, J., Lemal, D.M. "Octachloroazulene", J. Am Chem. Soc., in press.

Thomas A. Spencer

 "Further Studies on the synthesis of 24(S),25-Epoxycholesterol. A New Efficient Preparation of Desmosterol", Spencer, T.A.; Li, D.; Russel, J.S.; Tomkinson, N.C.O.; Willson, T.M. J. Org. Chem. 2000, 65, 1919-1923.

"Pharmacophore Analysis of the Nuclear Oxysterol Receptor LXRa ", Spencer, T.A.; Li, D.; Russel, J.S.; Collins, J.L.; Bledsoe, R.K.; Consler, T.G.; Moore, L.B.; Galardi, C.M.; McKee, D.D.; Moore, J.T.; Watson, M.A.; Parks, D.J.; Lambert, M.H.; Willson, T.M. J. Med. Chem., 2001, 44, 886-897.

Dennis L. Wright
  1. “Synthesis of Functionalized Pyrans by Domino Metathesis Reaction of Oxabicyclo Derivatives: Dramatic Effect of Remote Substituents on Reactivity and Selectivity” Usher, L.C.; Jimenez-Estrella, M.; Ghiviriga, I.; Wright, D.L. Angewandte Chemie, International Edition, 2002 , 4742-4744.
  2. A Two-Step Electrochemical Annulation for the Assembly of Polycyclic Systems” Whitehead, C.R.; Sessions, E.H.; Ghiviriga,    I.; Wright, D.L. Organic Letters, 2002 , 3763-5.
Harvard University Elias J. Corey 1."The Logic of Chemical Synthesis: Multistep Synthesis of Complex Carbogenic Molecules (Nobel Lecture)," E.J. Corey, Angew. Chem. Int. Ed. Engl., 30, 455 (1991).

2. "The Origin of Greater Than 200 : 1 Enantioselectivity in a Catalytic Diels-Alder Reaction as Revealed by Physical and Chemical Studies," E.J. Corey, T.-P. Loh, T.D. Roper, M.D. Azimioara, and M.C. Noe, J. Am. Chem. Soc., 114, 8290 (1992).

3. "Total Synthesis of Lactacystin," E.J. Corey and G.A. Reichard, J. Am. Chem. Soc., 114, 10677 (1992).

4. "Enantioselective Total Synthesis of Miroestrol," E.J. Corey and L.I. Wu, J. Am. Chem. Soc., 115, 9327 (1993).

5. "Rigid and Highly Enantioselective Catalyst for the Dihydroxylation of Olefins Using Osmium Tetraoxide Clarifies the Origin of Enantiospecificity," E.J. Corey and M.C. Noe, J. Am. Chem. Soc., 115, 12579 (1993).

Yoshito Kishi

1."Total Synthesis of Halichondrin B and Norhalichondrin B," T.D. Aicher, K.R. Buszek, F.G. Fang, C.J. Forsyth, S.H. Jung, Y. Kishi, M.C. Matelich, P.M. Scola, D.M. Spero, and S.K. Yoon, J. Am. Chem. Soc., 114, 3162 (1992).

2. "Structural Basis of Protein Kinase C Activation by Diacylglycerols and Tumor Promoters," R.R. Rando and Y. Kishi, Biochemistry, 31, 2211 (1992).

3. "Preferred Solution Conformation of Marine Natural Product Palytoxin and of C-Glycosides and Their Parent Glycosides," Y. Kishi, Pure Appl. Chem., 65, 771 (1993).

4. "Novel Structure Elucidation of AAL Toxin TA Backbone", C.D. Boyle, J.-C. Harmange, and Y. Kishi, J. Am. Chem. Soc., 116, 4995 (1994).

5. "Synthesis of Palytoxin from Palytoxin Carboxylic Acid", E.M. Suh and Y. Kishi, J. Am. Chem. Soc., 116, 11205 (1994)
David A. Evans Ni(II)–bis[(R,R)-N,N’-Dibenzylcyclohexane-1,2-diamine]Br2 Catalyzed Enantioselective Michael Additions of 1,3-Dicarbonyl Compounds to Conjugated Nitroalkenes," David A. Evans* and Daniel Seidel J. Am. Chem. Soc., 2005, 127, In Press

"Complex Aldol Reactions for the Construction of Dense Polyol Stereoarrays: Synthesis of the C33-C36 Region of Aflastatin A," David A. Evans,* Frank Glorius, and Jason D. Burch Organic Lett., 2005, 7, ASAP

"Enantioselective Syn-Selective Scandium-Catalyzed Ene Reactions," David A. Evans and Jimmy Wu J. Am. Chem. Soc., 2005, 127, 8006-8007

Eric N. Jacobsen
  1. Sammis, G. M.; Danjo, H.; Jacobsen, E. N. "Cooperative Dual Catalysis: Application to the Highly Enantioselective Conjugate Cyanation of Unsaturated Imides," J. Am. Chem. Soc. 2004, 126, 9928-9929.
  2. Taylor, M. S.; Jacobsen, E. N. "Highly Enantioselective Catalytic Acyl-Pictet-Spengler Reactions," J. Am. Chem. Soc. 2004, 126, 10558-10559.
  3. Vanderwal, C. D.; Jacobsen, E. N. "Highly Enantioselective Hydration of α,β-Unsaturated Imides by Al-Catalyzed Conjugate Addition of Oxime Nucleophiles," J. Am. Chem. Soc. 2004, 126, 14724-14725.
Daniel Kahne Glycosylation of Glycopeptides: A Comparison of Chemoenzymatic and Chemical Methods. C. Leimkuhler, Z. Chen, R. Kruger, M. Oberthuer, W. Lu, C. T. Walsh, and D. Kahne, Tetrahedron: Asymmetry 2005,16, 599-603.

A Practical Method for the Stereoselective Generation of beta-2-Deoxy Glycosyl Phosphates. M. Oberthuer, C. Leimkuhler and D. Kahne, Org. Lett.2004, 6, 2873-2876.
David R. Liu "Directing Otherwise Incompatible Reactions in a Single Solution Using DNA-Templated Organic Synthesis" Calderone, C. T.; Puckett, J. W.; Gartner, Z. J.; Liu, D. R. Angew. Chem. Int. Ed. 41, 4104-4108 (2002). This work is featured as an Editor's Choice in Science 298 [5598], 1517 (2002). This paper describes a new mode of controlling reactivity in a DNA-templated format that is not possible using conventional synthesis approaches.

"Multistep Small-Molecule Synthesis Programmed by DNA Templates" Gartner, Z. J.; Kanan, M. W.; Liu, D. R. J. Am. Chem. Soc., 124, 10304-10306 (2002). News stories describing this work appear in Chem. & Eng. News 80 [34] 12 (2002), and in Science, 300, 242 (2003). This paper describes the development of linker and purification strategies that enable the products of DNA-templated reactions to serve as starting materials for subsequent DNA-templated transformations. These findings enable DNA sequences to be translated into structures of useful complexity.

"DNA-Templated Functional Group Transformations Enable Sequence-Programmed Synthesis Using Small-Molecule Reagents" Sakurai, K.; Snyder, T. M.; Liu, D. R. J. Am. Chem. Soc. 127, 1660-1661 (2005).

Andrew G. Myers  A Method For the Rapid Synthesis of Highly Functionalized 2-Hydroxy-1-Naphthoates. Syntheses of the Naphthoic Acid Components of Neocarzinostatin Chromophore and N1999A2. Nan Ji, Brad M. Rosen, and Andrew G. Myers Org Lett. 2004, 6, 4551.

A Convergent Enantioselective Route to Structurally Diverse 6-Deoxytetracycline Antibiotics. Mark G. Charest, Christian D. Lerner, Jason D. Brubaker, Dionicio R. Siegel and Andrew G. Myers, Science 2005, 308, 395.

A General Procedure for the Esterification of Carboxylic Acids with Diazoalkanes Generated In Situ by the Oxidation of N-tert-Butyldimethylsilylhydrazones with (Difluoroiodo)benzene. Michael E. Furrow and Andrew G. Myers J. Am. Chem. Soc. 2004, 126, 12222.
Matthew Shair Biomimetic Synthesis of (-)-Longithorone A. Layton, M. E.; Morales, C. M.; Shair, M. D.
J. Am. Chem. Soc. 2002, 124, 773-775.
Use of Biomimetic Diversity-Oriented Synthesis to Discover Galanthamine-Like Molecules
with Biological Properties Beyond Those of the Natural Product. Pelish, H. E.; Westwood, N. J.;
Feng, Y.; Kirchhausen, T.; Shair, M. D. J. Am. Chem. Soc. 2001, 123, 6740-6741.
 Reaction Microarrays: A Method for Determining the Enantiomeric Excess of Thousands of
Samples. Korbel, G.; Lalic, G.; Shair, M. D. J. Am. Chem. Soc. 2001, 123, 361-362. For
commentaries, see: Chem. & Eng. News 2001, 1/15, 9. And Chemistry&Industry 2001, 4, 119.
Selected as one of the Chemistry Highlights of 2001 by C&E News: Chem. & Eng. News 2001,
12/10, 51.
M.-Christina White  
George Whitesides  
University of Pennsylvania William P. Dailey T. Martinu and W.P. Dailey " Facile One-Pot Preparation of 3-Chloro-2-(chloromethyl)propene and an Ab Initio Study of the Deamination Reaction of Nitrosoaziridine", J. Org. Chem. 2000, 65(20); 6784-6786.
Ralph F. Hirschmann Effects of Heterocyclic Aromatic Substituents on Binding Affinities at Two Distinct Sites of Somatostatin Receptors. Correlation with the Electrostatic Potential of the Substituents, V. Prasad, E.T. Birzin, C.T. McVaugh, R.D. van Rijn, S.P. Rohrer, G. Chicchi, D.J. Underwood, E.R. Thornton, A.B. Smith, III, R. Hirschmann, J. Med. Chem. 2003, 46, 1858-1869.

Design and Synthesis of Novel Scaffolds for Drug Discovery: Hybrids of β-D-Glucose with 1,2,3,4-Tetrahydro-benzo[e][1,4]diazepin-5-one, the Corresponding 1-Oxazepine, and 2- and 4-Pyridyldiazepines, L. Abrous, J. Hynes, Jr., S.R. Friedrich, A.B. Smith, III and R. Hirschmann, Org. Lett., 2001, 3, 1089-1092.

Synthesis of a Substance P Antagonist with a Somatostatin Scaffold: Factors Affecting Agonism/Antagonism at GPCRs and the Role of Pseudosymmetry, J. Liu, D. Underwood, M.A. Cascieri, S.P. Rohrer, L-D. Cantin, G. Chicchi, A.B. Smith, III and R. Hirschmann, J. Med. Chem., 2000, 43, 3827-3831.  
Madeleine M. Joullie B. Liang, et al. "Total Syntheses and Biological Investigations of Tamandarins A and B and Tamandarin A Analogs." J. Am. Chem. Soc. 2001, 123, 4469-4474.

D. Xiao et al. "Total Synthesis of a Conformationally Constrained Didemnin B. Analog." J. Org. Chem., 2001, 66, 2734-2742.
Marisa C. Kozlowski Phuan, P.-W.; Ianni, J. C.; Kozlowski, M. C. "Is the A-Ring of Sparteine Essential for High Enantioselectivity in the Asymmetric Lithiation-Substiution of N-Boc-pyrrolidine? J. Am. Chem. Soc. 2004, 126, 15473-15479.

3) Lipkowitz, K. B.; Kozlowski, M. C. "Understanding Stereoinduction in Catalysis via Computer: New Tools for Asymmetric Synthesis" Synlett 2003, 1547-1565. 

4) Li, X.; Hewgley, J. B.; Mulrooney, C.; Yang, J.; Kozlowski, M. C. "Enantioselective Oxidative Biaryl Coupling Reactions Catalyzed by 1,5-Diazadecalin Metal Complexes:  Efficient Formation of Chiral Functionalized BINOL Derivatives" J. Org. Chem. 2003, 68, 5500-5511. 
Gary A. Molander

G. A. Molander, B. Biolatto, “Palladium Catalyzed Suzuki-Miyaura Cross-Couping Reactions of Potassium Aryl- and Heteroaryltrifluoroborates”, J. Org. Chem., 68, 4302-4314 (2003).

M. Shenglof, D. Gelman, B. Heymer, H. Schumann, G. A. Molander, J. Blum, “Cross-Coupling of Aryl Halides and Triflates with Intramolecularly Stabilized Group 13-Metal Alkylating Reagents in the Presence of Mixed-Metal Catalysts”, Synthesis, 302-306 (2003).

G. A. Molander, M. Ribagorda, “Expanding Organoboron Chemistry. Epoxidation of Potassium Organotrifluoroborates”, J. Am. Chem. Soc., 125, 11148-11149 (2003).

G. A. Molander, C. -S. Yun, M. Ribagorda, “B-Alkyl Suzuki-Miyaura Cross-Coupling Reactions with Air Stable Potassium Alkyltrifluoroborates”, J. Org. Chem., 68, 5534-5539 (2003).

G. A. Molander, K. M. George, L. G. Monovich, “Total Synthesis of (+)-Isoschizandrin Utilizing a Samarium(II) Iodide Promoted 8-Endo Ketyl-Olefin Cyclization”, J. Org. Chem., 68, 9533-9540 (2003).

  1. V. Percec, T. Guliashvili, A. V. Popov, E. Ramirez-Castillo, L. A. Hinojosa-Falcon. "Ultrafast synthesis of poly(methyl methacrylate)-b-poly(vinyl chloride)-b-poly(methyl methacrylate) block copolymers by the Cu(0)/tris(2-dimethylaminoethyl)amine-catalyzed living radical block copolymerization of methyl methacrylate initiated with alpha,omega-di(iodo)poly(vinyl chloride) in the presence of dimethyl sulfoxide at 25 degrees C." J. Polym. Sci.: Part A: Polym. Chem.43, 1660-1669(2005).
  2. V. Percec, T. Guliashvili, A. V. Popov, E. Ramirez-Castillo, J. F. J. Coelho, L. A. Hinojosa-Falcon. "Accelerated synthesis of poly(methyl methacrylate)-b-poly(vinyl chloride)-b-poly(methyl methacrylate) block copolymers by the CuCl/tris(2-dimethylaminoethyl)amine-catalyzed living radical block copolymerization of methyl methacrylate initiated with alpha,omega-di(iodo)poly(vinyl chloride) in dimethyl sulfoxide at 90 degrees C."J. Polym. Sci.: Part A: Polym. Chem.43, 1649-1659(2005).
Amos B. Smith

Smith, Amos B.; Pitram, Suresh M.; Boldi, Armen M.; Gaunt, Matthew J.; Sfouggatakis, Chris; Moser, William H. Multicomponent Linchpin Couplings. Reaction of Dithiane Anions with Terminal Epoxides, Epichlorohydrin, and Vinyl Epoxides: Efficient, Rapid, and Stereocontrolled Assembly of Advanced Fragments for Complex Molecule Synthesis. Journal of the American Chemical Society (2003), 125 (47), 14435-14445.

Smith, Amos B.; Freeze, B. Scott; Brouard, Ignacio; Hirose, Tomoyasu. A Practical Improvement, Enhancing the Large-Scale Synthesis of (+)-Discodermolide: A Third-Generation Approach. Organic Letters (2003), 5 (23), 4405-4408.

Smith, Amos B.; Pitram, Suresh M.; Fuertes, Michael J. (+)-Rimocidin Synthetic Studies. Construction of an Advanced C(1-18) Polyol Fragment. Organic Letters (2003), 5(15), 2751-2754.

Smith, Amos B.; Pitram, Suresh M.; Fuertes, Michael J. (+)-Rimocidin Synthetic Studies. Construction of an Advanced C(1-18) Polyol Fragment. Organic Letters (2003), 5 (15), 2751-2754.

Smith, Amos B.; Cho, Young Shin; Pettit, G. Robert; Hirschmann, Ralph. Design, synthesis, and evaluation of azepine-based cryptophycin mimetics. Tetrahedron (2003), 59 (35), 6991-7009.
 
Edward R. Thornton Turowski, M.; Yamakawa, N.; Meller, J.; Kimata, K.; Ikegami, T.; Hosoya, K.; Tanaka, N.; Thornton, E. R. J. Am. Chem. Soc. 2003, 125, 13836-13849. "Deuterium Isotope Effects on Hydrophobic Interactions: The Importance of Dispersion Interactions in the Hydrophobic Phase."

Prasad, V.; Birzin, E. T.; McVaugh, C. T.; van Rijn, R. D.; Rohrer, S. P.; Chicchi, G.; Underwood, D. J.; Thornton, E. R.; Smith, A. B., III; Hirschmann, R. J. Med. Chem. 2003, 46, 1858-1869. "Effects of Heterocyclic Aromatic Substituents on Binding Affinities at Two Distinct Sites of Somatostatin Receptors. Correlation with the Electrostatic Potential of Substituents."
Jeffrey D. Winkler Y. Kwak, J. Winkler, "Synthesis of 6-Aza-Bicyclo[3.2.1]Octan-3-Ones via Vinylogous Imide Photochemistry: An Approach to the Synthesis of the Hetisine Alkaloids," J. Am. Chem. Soc. 2001, 113, 7429-7430.

J. Winkler, E. Piatnitski, J. Mehlmann, J. Kasparec, P. Axelsen, "Design and Synthesis of Novel Foldamers Based on an Anthracene Diels-Alder Adduct," Angew. Chem. Int. Ed. Engl., 2001, 113, 765-767.

J. Winkler, E. Doherty, " The First Total Synthesis of (+)-Saudin," J. Am. Chem. Soc. 1999, 121, 7425-7426.
Princeton University John T. Groves H. Zhou, J. T. Groves, "Hemodextrin: A self-assembled cyclodextrin-porphyrin protein model compound that binds dioxygen." Abstr. Pap. Am. Chem. S 224: 117-INOR Part 1 AUG 18 2002

E. Fadeev, M. Luo, J. T. Groves, "Synthesis and characterization of acinetoferrin, schizokinen and their metal complexes." Abstr. Pap. Am. Chem. S 224: 099-INOR Part 1 AUG 18 2002

H. Zhou, J. T. Groves, "Synthesis and characterization of a self-assembled hemoprotein model compound with a pyridyl axial ligand." Abstr. Pap. Am. Chem. S 224: 269-ORGN Part 2 AUG 18 2002
Chulbom Lee
  • "Allylic Etherification via Ir(I)/Zn(II) Bimetallic Catalysis," J. P. Roberts and C. Lee, Org. Lett., 7, ASAP (2005).
  • "Iridium-catalyzed selective N-allylation of hydrazines," R. Matunas, A. J. Lai and C. Lee, Tetrahedron, 61, 6298-6308 (2005).
  • "Total Synthesis of Kendomycin: A Macro-C-Glycosidation Approach," Y. Yuan, H. Men and C. Lee, J. Am. Chem. Soc., 126, 14720-14721 (2004).
  • "Stereoselective Palladium-Catalyzed O-Glycosylation Using Glycals," H. Kim, H. Men and C. Lee, J. Am. Chem. Soc., 126, 1336-1337 (2004).
  • "A Mild and Efficient Method for the Stereoselective Formation of C-O Bonds: Palladium-Catalyzed Allylic Etherification Using Zinc(II) Alkoxides," H. Kim and C. Lee, Org. Lett., 4, 4369-4371 (2002).
Martin F. Semmelhack

1.Semmelhack, M. F.; Campagna, S. R.; Federle, M. J.; Bassler, B. L.; Org. Lett. 2005; 7(4); 569-572. “An Expeditious Synthesis of DPD and Boron Binding Studies.”
2. Semmelhack, M. F.; Chlenov, A. “AreneCr(CO) 3 ComplexesAromatic Nucleophilic Substitution.” in “Transition Metal Arene Pi Complexes in Organic Synthesis and Catalysis.” Kundig, E. P. ed.; Springer-Verlag, Berlin, 2004, pp 43-70.16. M. F. Semmelhack and P. Shanmugam, Tetrahedron Lett., 41, 3567 (2000). "Development of an Approach to the Synthesis of the Plakortones."
3. Semmelhack, M. F.; Chlenov, A. “AreneCr(CO) 3 Complexes: Arene Lithiation/Rea ction with Electrophiles.” in “Transition Metal Arene Pi Complexes in Organic Synthesis and Catalysis.” Kundig, E. P. ed.; Springer-Verlag, Berlin, 2004, pp 21-42. 4. Miller, S. T.; Xavier, K. B.; Campagna, S. R.; Taga, M. E.; Semmelhack, M. F.; Bassler, B., L.; Hughson, F. M. Molecular Cell, 2004, 15, 677-687. “Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2.”
Erik J. Sorensen "Design, Synthesis and Reactivity of 1-Hydrazinodienes for Use in Organic Synthesis", G. M. Sammis, E. M. Flamme, H. Xie, D. M. Ho, E. J. Sorensen, J. Am. Chem Soc. 2005, 127, 8612-8613.

"Palladium-Catalyzed Ring-Forming Aminoacetoxylation of Alkenes", E. J. Alexanian, C. B. Lee, E. J. Sorensen, J. Am. Chem Soc. 2005, 127, 7690-7691.

"Protein-Reactive Natural Products", C. Drahl, B. F. Cravatt, E. J. Sorensen, Angew. Chem. Int. Ed. 2005, accepted.

"A remarkable architectural self-construction process is discovered in a synthesis of FR182877", C. D. Vanderwal, E. J. Sorensen, an invited contribution to Strategies and Tactics in Organic Synthesis, M. Harmata, Ed., Academic Press: New York, 2004.

"A dash of proline makes things sweet", E. J. Sorensen, G. M. Sammis, Science 2004, 305, 1725-1726.
Edward C. Taylor
  • Synthesis of Herbicidal 2-Aryl-4(3H)-pyrimidinones (with C. M. Tice, L. M. Bryman, R. C. Roemmele, Ping Zhou, J. Jurczak and A. Jezewski) IN Synthesis and Chemistry of Agrochemicals VI, American Chemical Society Symposium Series, Vol. 800, 2002, pp. 51-60.
  • Synthesis and Bridgehead Reactions of 9-Substituted 5,6,7,8,9,10-Hexahydro-5,9-methanopyrimido[4,5-b]azocin-4(3H)-ones (with Beena Bhatia), Heterocycles, 61, 113-123 (2003)
  • A New and Efficient Synthesis of Pyrrolo[2,3-d]pyrimidine Anticancer Agents: Alimta (LY231514, MTA), Homo-Alimta, TNP-351, and Some Aryl 5-Substituted Pyrrolo[2,3-d]pyrimidines (with Bin Liu), J. Org. Chem., 68, 9938-9947 (2003).
Yale University Jerome A. Berson
  • Chemical Creativity: Ideas from the Work of Woodward, Meerwein, and Hückel (book) (Wiley-VCH, 1999).
  • Kekulé Escapes, Popper Notwithstanding. Angew. Chem. Intl. Ed. Engl., 2000, 39, 3045.
  • Chemical Discovery and the Logicians’ Program: A Problematic Pairing (book) (Wiley-VCH, 2003).
H.H. Wasserman
  • H.H. Wasserman, A.K. Petersen, M. Xia, J. Wang, Pyrrole-Singlet Oxygen Reactions Leading to a,a'-bipyrroles. Synthesis of Prodigiosin and Analogs, Tetrahedron Letters 1999, 40, 7587.
  • H.H. Wasserman, M. Xia, A.J. Carr, W.T. Han, M.G. Siegel, Generation of Penems, Carbapenems and Aza Analogs of Cephems by the Addition of Heterocycles and Other Building Blocks to Azetinones, Tetrahedron 2000, 56, 5621.
  • H.H. Wasserman, J.-H. Chen, M. Xia, The Chemistry of Vicinal Tricarbonyls. Total Syntheses of Elastase Inhibitors YM-47141 and YM-47142, Helvetica Chimica Acta 2000, 83, 2607.
Kenneth B. Wiberg
  • "Substituent Effects. 7, Phenyl Derivatives. When is Fluorine a pi-Donor?" K. B. Wiberg and P. R. Rablen, J. Org. Chem. 1998, 63, 3722.
  • "A Transition State of Enanioselective Deprotonation of N-Boc-pyrrilidine with Isoropyllithium/(-)-sparteine," K. B. Wiberg and W. F. Bailey, Angew. Chem. Int., Ed. 2000, 39, 2127.
  • "Solvation and Structural Effects on the Stability of 10-X-Are-Complexes: A Computational Study," K. B. Wiberg, S. Sklenak and W. F. Bailey, J. Org. Chem. 2000, 65, 2014-2021.
David J. Austin
  • “Synthesis of 5'-Functionalized Adenosine: Suppression of Cyclonucleoside Formation” Liu, F.; Austin, D. J. Tetrahedron Lett. 2001, 42, 3153.
  • “An Improved Synthesis of (4S)-4,5-O-Isopropylidenepent-(2Z)-Enoate” Koenig, S. G.; Löwe, R. S.; Austin, D. J. Synth. Comm. 2002, 32,1379.
  • “The Cloning of Human Genes Using cDNA Phage Display and Small-Molecule Chemical Probes” Savinov, S. N.; Austin, D. J. Combinatorial Chemistry and High Throughput Synthesis 2001, 4, 593.
  • “Combinatorial Chemistry in Cancer Drug Development” Leonard, K. A.; Deisseroth, A.; Austin, D. J. The Cancer Journal 2001, 7, 79-83.
Craig Crews
 
  • Shotwell, J.B., Koh, B., Ndubuisi, M., Choi, H.W., Medina, E., Wood, J.L., C.M. Crews (2002) Novel Inhibitors of NF-kB Signalling: Design and Synthesis of a Biotinylated Isopanepoxydone Affinity Reagent. Bioorganic and Medicinal Chemistry Letters 12 (23): 3463-3466.
  • J. B. Shotwell, E.S. Krygowski, J. Hines, B. Koh, E.W. D. Huntsman, H. W. Choi, J.S. Schneekloth Jr., J. L. Wood, and C.M. Crews (2002) Total Synthesis of Luminacin D Organic Letters, 5;4(18):3087-9.
  • J.S. Schneekloth, Jr., F. Fonseca, M. Koldobskiy, A. Mandal, R. Deshaies, K. Sakamoto, and C. M. Crews (2004) Chemical Genetic Control of Protein Levels: Selective in vivo Targeted Degradation J. Am. Chem. Soc. (in press.)
Andrew D. Hamilton
  • Choi, K.; Hamilton, A. D. "Selective Anion Binding by a Macrocycle with Convergent Hydrogen Bonding Functionality". J. Am. Chem. Soc. 2001, 123, 2456-2457.
  • Orner, B. P.; Ernst, J. T.; Hamilton, A. D. "Towards Proteomimetics: Terphenyl Derivatives as Structural and Functional Mimics of Extended Regions of an a-Helix", J. Am. Chem. Soc. 2001, 123, 5382-5383.
  • Crespo, N.; Ohkanda, J.; Hamilton, A. D.; Sebti, S. M. "FTI-2153 inhibits bipolar spindle formation and chromosome aignment and causes prometaphase accumulation during mitosis of human lung cancer cells" J. Biol. Chem. 2001, 276, 16161-16167.
William L. Jorgensen
  • Validation of a Model for the Complex of HIV-1 Reverse Transcriptase with Sustiva through Computation of Resistance Profiles. R. C. Rizzo, D.-P. Wang, J. Tirado-Rives, and W. L. Jorgensen, J. Am. Chem. Soc., 122, 12898 (2000).
  • Estimation of Binding Affinities for HEPT and Nevirapine Analogs with HIV-1 Reverse Transcriptase via Monte Carlo Simulations. R. C. Rizzo, J. Tirado-Rives, and W. L. Jorgensen, J. Med. Chem., 44, 145 (2001).
J. Michael McBride Using Crystal Optics to Demonstrate Single-Layer Localization of a Solid-State Chain Reaction. Kevin L. Pate and J. M. McBride, Helv. Chim. Acta., 2000, 83, 2352-2362.
Glenn C. Micalizio
  • A. B. Bahadoor, A. Flyer, G. C. Micalizio, “A Pentenyl Dianion-based Strategy for Convergent Synthesis of Ene-1,5-Diols,” J. Am. Chem. Soc. 2005, 127, 3694.
  • G. C. Micalizio and S. L. Schreiber, “An Alkynylboronic Ester Annulation: Development of Synthetic Methods For Application to Diversity-Oriented Organic Synthesis,” Angew. Chem. Int. Ed. 2002, 41, 3272.
  • G. C. Micalizio and S. L. Schreiber, “A Boronic Ester Annulation Strategy for Diversity-Oriented Organic Synthesis,” Angew. Chem. Int. Ed. 2002, 41, 152.
Martin Saunders
  • Reversible Diels-Alder Addition to Fullerenes: A Study of Equilibria Using 3He NMR Spectroscopy. Guan-Wu Wang, Martin Saunders, R. James Cross, J. Am. Chem. Soc. 123, 256-259 (2001).
  • Insertion of Helium and Molecular Hydrogen through the Orifice of an Open Fullerene. Yves Rubin, Thibaut Jarrosson, Guan-Wu Wang, Michael D. Bartberger, K. N. Houk, Georg Schick, Martin Saunders, R. James Cross, Angew. Chem., Int. Ed. 40, 1543-1546 (2001).
Alanna Schepartz
 
  • Miniature Homeodomains:  High specificity without an N-terminal arm.  J.K. Montclare & A. Schepartz, J. Am. Chem. Soc. 2003, 125, in the press.
  • Helix macrodipole control of b3-peptide 14-helix stability in water.  S.A. Hart, A.B.F. Bahadoor, E.E. Matthews, & A. Schepartz, J. Am. Chem. Soc. 2003, 125, 4022-4023.
Dieter Söll
 
  • Curnow, A., Ibba, M. and Söll, D. (1996) "tRNA-dependent asparagine formation." Nature 382, 589-590.
  • Ibba, M., Morgan, S., Curnow, A.W., Pridmore, D.R., Vothknecht, U.C., Gardner, W., Lin, W., Woese, C.R. and Söll, D. (1997) "A euryarchaeal lysyl-tRNA synthetase: resemblance to class I synthetases." Science 278, 1119-1122.
  • Stathopoulos, C., Li, T., Longman, R., Vothknecht, U.C., Becker, H., Ibba, M. and Söll, D. (2000) "One polypeptide with two aminoacyl-tRNA synthetase activities." Science 287, 479-482.
  • Tumbula, D.L., Becker, H.D., Chang, W-Z. and Söll, D. (2000) "Domain-specific recruitment of amide amino acids for protein synthesis." Nature 407, 106-110.
Scott A. Strobel
  • G. W. Muth, L. Ortoleva-Donnelly and S. A. Strobel. A Single Adenosine with a Neutral pKa in the Ribosomal Peptidyl Transferase Center. Science 289, 947-50 (2000).
  • A. K. Oyelere and S. A. Strobel. Biochemical Detection of Cytidine Protonation within RNA. J. Amer. Chem. Soc. 42, 10259-10267 (2000).
Frederick E. Ziegler
  • Ziegler, F. E. ; Kover, R. X.; Yee, N. N. K., Studies Directed Toward the Synthesis of FS-2: Observations on the Fragmentation of Cyclobutylcarbinyl Radicals, Tetrahedron Lett., 2000, 41, 5155.
  • Ziegler, F. E.; Berlin, M. Y.; Lee, K.; Looker, A. R., Formation of 9,10-Unsaturation in the Mitomycins: Facile Fragmentation of b-Alkyl-b-aryl-a-oxo-g-butyrolactones, Organic Lett., 2000, 2, 3619.

 

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